TINY ORGANS, BIG IMPACT
Pioneering human models to predict clinical success.
Custom cell based models, predictive testing, bespoke batch manufacture.
Get reliable results every time with Cytochroma.
🌏Cytochroma’s advanced liver models are now available worldwide! 🌎
Cytochroma’s proprietary cryoprotectant and cutting-edge freezing methods preserve cell morphology, function and activity.
Ideal for safety pharmacology testing, high throughput screening and disease modelling.
High cytochrome P450 function is maintained for over 20 days and cells are drug inducible.
High protein levels of Albumin and low Alpha fetoprotein production are representative of mature hepatocytes.
Functionally polarised cells express high levels of Albumin, Hepatocyte nuclear factors (HNFα) and Matrix resistance protein 1 (MRP1).
Predicting success from molecule to market
Unexpected cardiac and hepatic adverse effects are the top two leading causes of discontinuation of clinical trials and withdrawal of drugs from the market.
Cytochroma provides predictive cell models from genetic backgrounds the FDA has highlighted as lacking in clinical trials. Bringing unique insight into how drugs will react early on in drug development.
Cytochroma’s accurate preclinical models predict toxicity earlier, reducing expensive late-stage failures, redirecting time and costs, and bringing safer drugs to market.
